He played all or part of seven seasons in Major League Baseball (MLB) for the San Diego Padres, New York Yankees, Detroit Tigers, and Texas Rangers between 1985 and 1992.

McCullers was an offensive lineman and defensive tackle while attending Tampa Catholic High School, but switched to baseball following an injury.

He became a free agent and signed a minor league contract with the Los Angeles Dodgers where he pitched for the Albuquerque Dukes and Calgary Cannons.

[2] He played football as an offensive lineman and defensive tackle until he experienced an arm injury and decided to focus on baseball.

[3] Playing for the school's baseball team with Tino Martinez and Rich Monteleone, Tampa Catholic won the Class 3A state championship in 1982.

[9] McCullers began the 1985 season with the Las Vegas Stars of the Class AAA Pacific Coast League (PCL).

[10] Due to an injury to Goose Gossage, the Padres promoted McCullers to the major leagues as a relief pitcher in August 1985.

[14] On October 24, 1988, the Padres traded McCullers, Stan Jefferson, and Jimmy Jones to the New York Yankees for Jack Clark and Pat Clements.

[16] McCullers got more regular work after the Yankees replaced Dallas Green as manager with Bucky Dent,[17] and he finished the 1989 season with a 4.57 ERA.

Continued numbness and loss of pulse in his hand led to another inpatient stay in the hospital and surgery to remove the clot from his wrist.

[23] He signed a minor league contract with the Los Angeles Dodgers in July,[24] and pitched for the Albuquerque Dukes of the PCL.