Landisville is an unincorporated community and census-designated place (CDP) in East Hempfield Township, Lancaster County, Pennsylvania, United States.

[3] The community was once part of the Salunga-Landisville CDP, before splitting into two separate CDPs for the 2010 census, the other being Salunga.

Landisville is located along Old Harrisburg Pike, 7 miles (11 km) northwest of Lancaster, the county seat.

Pennsylvania Route 283, a four-lane expressway, forms the northern edge of the community, with access from Pennsylvania Route 722, 2 miles (3 km) southeast of town, and from Spooky Nook Road, 1.5 miles (2.4 km) northwest of town, on the northern edge of Salunga.

PA 283 leads southeast to Lancaster and northwest 32 miles (51 km) to Harrisburg, the state capital.