CD98 is a glycoprotein[1][2] that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1).
LAT1 is a heterodimeric membrane transport protein that preferentially transports branched-chain (valine, leucine, isoleucine) and aromatic (tryptophan, tyrosine, phenylalanine) amino acids.
[3] LAT is highly expressed in brain capillaries (which form the blood–brain barrier) relative to other tissues.
[3] A functional LAT1 transporter is composed of two proteins encoded by two distinct genes:
This membrane protein–related article is a stub.