[8] SLC45A2 is also a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines.

[9] A similar sequence gene in medaka fish, 'B,' encodes a transporter that mediates melanin synthesis.

[15] In dogs a mutation to this gene causes white fur, pink skin, and blue eyes.

[16] SLC45A2 was identified as a melanoma tumor-associated antigen with high tumor specificity and reduced potential for autoimmune toxicity, and is currently in clinical development as a target for T-cell based immunotherapy.

[17] This article incorporates text from the United States National Library of Medicine, which is in the public domain.