Largs bay is bounded to the north by Walcot and Warwick Street, to the south by Wills, Hargrave and Union Streets and in the west and east by Gulf St Vincent and the centre of the Port River respectively.

It is located within the local government area of the City of Port Adelaide Enfield.

Largs Bay originally started as a private sub-division in Section 1069 in the cadastral unit of the Hundred of Port Adelaide.

The Largs Pier Hotel on the Esplanade was used as a historical landmark in earlier times by sailors.

The eastern side of the suburb, by the Port riverside is the location of three shipping berths, which are used by Caltex, BP and Mobil vessels.