Larissa State Airport "Thessaly" (Greek: Κρατικός Αερολιμένας Λάρισσας "Θεσσαλία") (IATA: LRA, ICAO: LGLR) was built in 1912.

Currently the airport is being used only by military aircraft of the Hellenic Air Force, whose 110th Combat Wing (110 Πτέρυγα Μάχης, 110 ΠΜ) is stationed there.

The airport is very close to the city and to the suburban railway line to Thessaloniki (3 km).

In May 2018, it was announced that US Air Force (USAF) MQ-9 Reaper drones were temporarily based at Larissa while their usual base in Africa was being updated, according to a Pentagon spokesman, Eric Pahon.

[1] US assistant secretary of state for European and Eurasian affairs A. Wess Mitchell also discussed the possibility of relocating a significant portion of US military assets to the premises.