Notably, he broke new ground as the first African to helm a reality TV show on MTV Africa "@Lasizwe: Fake It Till You Make It," garnering three successful seasons in less than two years.

His mother, Lindiwe Dambuza (died in 2016) was a 40-year-old nurse at Lesedi Private Hospital, in a relationship with his father, Menzi Mcunu.

[8] Before starting his career, Lasizwe's mother took him for television auditions on a weekly basis across Gauteng from primary school.

The urge to be on TV led him to post videos on Facebook, and ultimately create relatable South African content.

[9] His first breakout video, Ek Sal Doom Jou, which was a skit based on news reports of a controversial pastor that sprayed the faces of his congregants with insect repellent in church.

The deal followed after he had posted a video on his social media platforms that depicted his famed character "Nomatriquency" undergoing an interview for a position at GAME.

[21] In September 2021, he partnered with Steers in the #NomatriquencyxSteers campaign that saw his famed character Nomatriquency getting a job at the brand.

[23] On 1 April 2022, he starred on the e.tv television series Durban Gen.[24] In that same month, he was nominated for favourite personality at the 2022 DStv Mzansi Viewers' Choice Awards.

[30] In May 2024, Lasizwe was part of the panel for the Showmax and Laugh Africa Comedy, Roast of Minnie Dlamini.

[31] In December 2017, he was featured in Babes Wodumo and Ntando Duma's music video for the song "Jiva Phez'kombhede".

[6] Speaking about what inspired the show, he told Daily Sun that the idea came during some of the darkest times of his life: I was going through a lot of depression and wasn’t creative.

One day, I watched a show called Chicken Shop Date by a UK content creator and got inspired.

[41] In June 2024, Volvo Cars South Africa appointed Lasizwe and Thea Booysen as EX30 Champions to promote the company's newest electric vehicle, the EX30.