He is known for his lifelong research into the texts of the Fathers of the church and his critical editions of their works, including those of Cyprian.
A poor man, he was obliged to find a patron and entered the service of cardinal Pozzo, for whom he was Latin secretary.
He reformed the decretal of Gratian, at the wish of Pope Pius IV, which was published under Gregory XIII.
After his death, the chapter of the Cathedral of Viterbo acquired Latini's important library which contained many annotated copies.
The other was Bibliotheca sacra et profana, sive observationes, correctiones, conjecturae, et variae lectiones.