In 2024, she changed her surname to the gender neutral form to be distinguished from another WTA Tour tennis player, Russian Liudmila Samsonova, with whom she shared the same abbreviated name (L.

[2] A member of TK Sparta Prague, Samson won her first junior title as a 13-year-old at a J5 event in Prostějov in an October 2021, without dropping a set.

[6] In June 2024, she reached the final of the French Open girls' singles tournament but lost to compatriot Tereza Valentová.

[7] Defending the Wimbledon girls' doubles title alongside Kovačková in 2024, they lost in the quarterfinals to Mika Stojsavljevic and Mingge Xu.

[9] Given a wildcard entry into the 2024 Prague Open, Samson became the first player born in 2008 or later to win a WTA Tour main-draw match when she defeated qualifier Tara Würth in straight sets in the first round.