Laurentius taught his son Latin and Greek, He later studied under Justus Samuel Scharschmidt and at Pastor Glück's Lutheran school in the German settlement in Moscow.

[1] In 1706, he began to attend university at Halle, then Oxford and finally Leiden, where he studied under Herman Boerhaave,[2] defended his thesis, De secretione animali, in 1713 and received a medical degree in 1714.

He continued his studies in Paris and Amsterdam (with Frederik Ruysch, from whom he bought anatomical specimens on behalf of the Russian government for the Kunstkamera).

After his return to St. Petersburg, Peter the Great sent him to the Olonets Governorate to study the Marcial mineral springs in Kondopozhsky District.

He remained president of the academy until 1733 and returned to St. Petersburg, where he lived in the palace of the Empress' sister, Catherine Ivanovna, Duchess of Mecklenburg.

The Empress ordered an investigation of Blumentrost; no fault was found on his part, but by 19 June he had been stripped of his positions and income and expelled from St. Petersburg.