Lazaros curled a free kick over the top for Bologna before being denied by another brilliant save with 15 minutes to go after again jinking past defenders and letting loose.

Two minutes afterwards, the man of the match involved in everything was at the centre of controversy when the referee adjudged Daniele Dessena to have pushed him to the ground inside the box.

[5] On 16 May 2014, there was tension in the training campus at Bologna, a few days after the last challenge at the Olimpico against Lazio ending a disappointing season that led to relegation to Serie B.

[9][10] In January 2015, the interest of Hellas Verona in signing Argentinian offensive midfielder and winger Juan Sánchez Miño from Torino, leads the Gialloblù to offer him to i Granata the loan of Greek international same role player Lazaros Christodoulopoulos in exchange, according to Sky Sport Italia.

On 14 September 2017, he sealed the score in the second half with a direct free kick as AEK won 2–1 after an impressive performance against Rijeka at his first matchday of 2017–18 UEFA Europa League group stage.

[19][20] On 18 September 2017, AEK won 1–0 against newly promoted Super League club Lamia, at Peristeri Stadium, thanks to Christodoulopoulos, coming from the bench, scoring the goal of the match at 81', that brought the team of Manolo Jimenez on the top of the table, with 10 points after 4 games.

[23] On 27 January 2018, Christodoulopoulos opened the scoring for Manolo Jiménez's team after 40 minutes at the Olympic Stadium in a 2–0 home win against Lamia.

[24] On 7 February 2018, he opened the score in a 2–1 home Greek Cup win game against rivals Olympiacos, helping AEK to be promoted to the semi-finals.

[25] On 11 February 2018, Christodoulopoulos scored the only goal with a penalty kick four minutes after he entered in the field, beating Asteras Tripolis 1–0 at the Olympic Stadium to move one point clear of PAOK at the summit.

On 14 May 2018, AEK decided to put Christodoulopoulos in the out-of-favour list due to the player perceiving the club's contract renewal talks as 'threats' and being in discussions with rivals Olympiacos over a potential career move.

Christodoulopoulos opened the score by heading in brilliantly from a precise Omar Elabdellaoui cross, and in the second was in the right place to ram the ball home following Roderick Miranda’s header after Jagoš Vuković had hit the crossbar with a shot.

The FIFA Puskas Award is given out to the player who scored the best goal of the season and the international winger struck a beautiful free-kick from distance into the top right corner, giving opposing goalkeeper Stefanos Kapino no chance whatsoever.

[39] On 8 November 2018, Christodoulopoulos scored with a right footed shot from the centre of the box to the bottom left corner, after an assist by Kostas Fortounis with a cross in a hammering 5–1 win game against F91 Dudelange in the Europa League group stage.

[42] On 17 February 2019, after receiving an injury against rivals AEK Athens, Christodoulopoulos ruptured the anterior cruciate ligament in his left knee, meaning he sat on the sidelines for at least six months.

[43] On 22 December 2019, after a very difficult year for the defender marred by injury (309 days to be exact), Christodoulopoulos returned to action in an away game against Volos.

[45] On 5 June 2020, two days before the restart of the Super League playoffs, after an 80-days COVID-19 break Lazaros Christodoulopoulos received yet another injury blow, with the Olympiacos winger suffering a ligament rupture in his right knee.

[46] On 28 September 2020, Atromitos completed a great transfer move, as it announced the acquisition of the 33-year-old midfielder, who had signed a year contract for an undisclosed fee.

[50] On 26 August 2021, Christodoulopoulos helped Anorthosis Famagusta with two goals in seven minutes against Hapoel Beer Sheva, to qualify for the Europa Conference League group stage.

[51] On 25 November 2021, Anorthosis achieved the historic first victory of a Cypriot team in the Conference League group stage, where thanks to an astonishing 27th minute goal by Christodoulopoulos they prevailed 1–0 over undefeated Gent.

Fernando Santos' team went ahead in the 20th minute through Christodoulopoulos' strike who headed the only goal as Greece secured a well-deserved 1–0 victory over Lithuania in the 2014 World Cup qualifier which kept them in touching distance of Group G leaders Bosnia-Herzegovina.