Lebuh Ayer Keroh, Federal Route 143, also known as Lebuhraya Ayer Keroh or Ayer Keroh Avenue, is the main dual-carriageway highway that connects Malacca City of Malacca, Malaysia to the North–South Expressway via Ayer Keroh Interchange.

Ayer Keroh, the main satellite town of Malacca City is located along the road.

Lebuh Ayer Keroh used to be State Motorway M31 before being recommissioned by Malaysian Public Works Department (Jabatan Kerja Raya (JKR)).

[1] The Kilometre Zero of the Federal Route 143 starts at Jalan Durian Tunggal junctions near Ayer Keroh toll plaza of the Ayer Keroh Interchange.

At most sections, the Federal Route 143 was built under the JKR R5 road standard, with a speed limit of 90 km/h.