Lecania leprosa is a species of saxicolous (rock-dwelling), crustose lichen in the family Ramalinaceae.

The lichen was formally described as a new species in 2008 by Rikke Reese Næsborg and Jan Vondrák.

The type specimen was collected from Devín (Carpathian Mountains, Slovakia), where it was found growing on the mortar of a northwest-exposed wall.

The species epithet leprosa means "scurfy" or "scaley", and refers to the form of the lichen thallus.

[1] Lecania leprosa has been recorded from Austria, Czech Republic, Romania, and Slovakia, where it grows on concrete, mortar, and limestone.