Lee Jesse Gamble (June 28, 1910 – October 5, 1994) was an American professional baseball player.

He was an outfielder over parts of four seasons (1935, 1938–40) with the Cincinnati Reds.

He made only one error in 135 total chances in 77 games at the outfield for a .993 fielding percentage.

He was born in Renovo, Pennsylvania and later died in Punxsutawney, Pennsylvania at the age of 84.

This biographical article relating to an American baseball outfielder born in the 1910s is a stub.