She debuted as a child actress in 1997 and was best known for her roles in Dae Jang Geum (2003), When I Turned Nine (2004), Lovely Rivals (2004), and The Wonder Years (2007).

She is best known for her leading roles in The Crowned Clown (2019), The Red Sleeve (2021), The Law Cafe (2022), The Story of Park's Marriage Contract (2023), and What Comes After Love (2024).

[6][7] As she entered her early twenties, Lee also appeared in the television series Puberty Medley,[8] Missing You[9] and Goddess of Marriage,[10] as well as films Horror Stories 2 and Hot Young Bloods.

[14][15][16] Lee gained increased popularity after starring in the family drama The Gentlemen of Wolgyesu Tailor Shop (2016), where she received favourable reviews.

[20] Lee then starred in the fantasy romantic comedy drama A Korean Odyssey by the Hong sisters,[21] and was praised for her portrayal of three different characters.