Leiomyoma

A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%).

Polycythemia may occur due to increased erythropoietin production as part of a paraneoplastic syndrome.

Uterine lipoleiomyomata have been observed together with ovarian and other pathologies and some of them may develop into liposarcoma.

However, a case was reported in absence of associated immunodeficiency at Monash Hospital in Melbourne, Australia, in a healthy 39-year-old woman with no symptoms.

[7] Although leiomyoma is the most common benign esophageal tumor, malignant carcinoma is still 50 times more likely.

Leiomyoma enucleated from a uterus. External surface on left; cut surface on right.
Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei
Immunohistochemistry for β-catenin in uterine leiomyoma , which is negative as there is only staining of cytoplasm but not of cell nuclei. This is a consistent finding, which helps in distinguishing such tumors from β-catenin positive spindle cell tumors. [ 1 ]