A native of the Bronx, Weinrib got his start in show business working with Spike Jones, then later in The Billy Barnes Revue.

He made guest appearances on The Dick Van Dyke Show, The Many Loves of Dobie Gillis, Burke's Law, The Munsters, Happy Days and Adam-12.

Starting with The Flintstones where he provided the dialogue for Jimmy Darrock, Weinrib provided numerous voices for such animated series as Inch High, Private Eye, The New Adventures of Batman, Tarzan and the Super 7, and Hong Kong Phooey.

He also voiced a secretary bird and king Leonidas the lion in the animated sequence of the Disney film Bedknobs and Broomsticks.

He also lent his voice to Superman in 1970 for a Sesame Street sketch of a lecture about words beginning with "S" which happened to be the character's favorite letter of the alphabet.

Weinrib again voiced the Man of Steel, and his alter-ego Clark Kent, for a 1972 episode of The Brady Kids, "Cindy's Super Friend".

Weinrib voiced Davey Jones' Uncle Sedgwick, Hotel Desk Clerk and Shaggy's Great-Uncle Nathaniel on The New Scooby-Doo Movies.

("Winky Blintz" in "The Off-Broadway Affair", 1966) Happy Days ("Duke" in "Ritchie's Cup Runneth Over", 1974), and on two episodes of Adam-12 in 1973 and 1974 as Tony the police garage mechanic.

[3] For the Family Guy episode "Petarded", Seth MacFarlane explained on the Season 4 DVD commentary he wanted to use Weinrib to voice Timer for a cutaway gag, but Weinrib was suffering from failing health when "Petarded" was being produced, and as MacFarlane explained, he "didn't remember doing it" after the recorded audio was played back for him later.