In 1933, Krzycki was elected chairman of the national executive board of the Socialist Party of America, succeeding the lately deceased Morris Hillquit.

One first-hand account stated that he knew beforehand that the police captain was a "sadist" and stayed on-stage, trying in vain to dissuade the protests from going forward.

[6] Krzycki was also a key figure in organizing the 1937 strike against Ford Motor Company, and shares a historic image leading the strikers with labor leaders Richard Frankensteen and Ed Hall.

After news of the 1940 Katyn Massacre emerged, Krzycki's ASC broke with the Polish government in exile in London and stood with the Soviets, their Committee of Polish Patriots (a precursor to the post-war, Soviet-backed Polish government, and the Soviet-proposed changes to Poland's borders to the west and east Both the FBI and OSS and then CIA followed ASC activities, which later came to question before Congress and led to Krzycki's resignation and by organization's end by 1951.

[8][9] In 1944, Krzycki, by then "a noted one-time socialist leader," also became president of the American Polish Labor Council (APLC), appended to the CIO PAC to support Franklin Delano Roosevelt's 1944 presidential campaign.