He was a literary and drama critic for The Brooklyn Eagle and the Saturday Review of Literature before moving to Hollywood.
[4] Spigelglass got his start collaborating on the script for Erich von Stroheim's Walking Down Broadway at Fox Films.
[10] At Universal, he wrote for Letter of Introduction (1938), Service de Luxe (1938), Unexpected Father (1940), Private Affairs (1940), and The Boys from Syracuse (1940).
[14] At RKO, Spigelglass wrote The Big Street (1942), based on a Runyon story, and They Got Me Covered (1942) for Bob Hope.
[15] Spigelgass served as a lieutenant colonel in World War II and, with Frank Capra, planned and produced Army and Navy Screen Magazine, a bi-weekly, filmed news update for American troops abroad.
[20] Spigelglass signed a long-term contract at MGM where he wrote Mystery Street (1950), which earned him an Oscar nomination.
He followed it with Night into Morning (1951), The Law and the Lady (1951), Because You're Mine (1952), Scandal at Scourie (1953), Athena (1954), and Deep in My Heart (1954).
He produced a documentary series titled MGM Parade, and wrote the musicals Ten Thousand Bedrooms (1957) and Silk Stockings (1957).
"[24] Spigelglass moved to New York where he wrote for TV shows such as Playhouse 90 and Climax!, including a story of the life of Helen Morgan.
[23] He wrote the film adaptation of Majority of One and the big screen version of Gypsy (1962) both directed by Mervyn Le Roy.
[30] Dear Me, The Sky Is Falling (1963) (originally titled Libby) had a short run despite starring Gertrude Berg.