Born in Arroyo Seco, Santa Fe, Biagini started his career at Newell's Old Boys in the Primera División, in 1993.

[2] Biagini signed for Atlético Madrid at just 18, being an important attacking element as the capital club won the double in his first year.

[3] He was mainly and regularly used as a substitute for compatriot Juan Esnáider and Kiko during his spell and, after a poor second season, moved to fellow league side CP Mérida in the summer of 1997, where he would be eventually relegated.

[4] Biagini then played five seasons with RCD Mallorca where, safe for his first year where he scored a career-best 11 goals (also helping the team to the final of the 1998–99 UEFA Cup Winners' Cup by scoring the 1–0 winner against Chelsea in the last-four's second leg, in a 2–1 aggregate victory),[5][6][7] he would be very scarcely used due to several injury problems,[5] also serving a six-month loan to England's Portsmouth in the First Division,[8] where he found the net against Millwall[9] and Wimbledon.

[10] Biagini returned to Spain and Mallorca for the 2002–03 campaign, being part of the side that won Copa del Rey – even though he did not appear in any matches – and being subsequently released.