Leptadrillia loria is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.

(Original description) The small, vitreous, semitranslucent shell has an elongate-conic shape..

In addition to the axial ribs the whorls are marked by fine incremental lines on the spire as well as the base.

The inner lip is appressed to the columella as a callus which extends up over the parietal wall, where it develops into a conspicuous nodule near the posterior angle.

[3] This species occurs in the demersal zone of the Caribbean Sea off Puerto Rico at depths between 274 m and 357 m.