Lesego Motsepe (28 April 1974 – 20 January 2014) was a South African actress, social activist[2] and singer best known for her role as Letti Matabane in Isidingo from 1998 to 2008.
[3] Motsepe grew up in Meadowlands, and attended Technikon Pretoria where she obtained a diploma in speech and drama.
At the age of 5, she acted in a mutton advertisement on television, which earned her the childhood nickname Nama Ya Nku (Setswana for "mutton").
[4] Although best known for her role as Lettie Matabane in Isidingo, in which she played the sister of her former real-life boyfriend Tshepo Maseko, she enjoyed stage acting, and she played the lover of Steve Biko in the play "Biko - Where the Soul Resides", and the starring role in a musical at the State Theatre about Brenda Fassie.
[5] She attracted significant controversy[6] in 2012 when she discontinued her antiretroviral therapy in favour of alternative medicine, as promoted by deceased former health minister Manto Tshabalala-Msimang.