Leslie Ann Charleson (February 22, 1945 – January 12, 2025) was an American actress, best known for her role as Monica Quartermaine on the ABC daytime soap opera General Hospital.

She had a supporting role in the 1973 science-fiction film The Day of the Dolphin and co-starred opposite Shelley Winters in the television thriller Revenge!

[5][6] On August 16, 1977, Charleson returned to daytime television with the role of Monica Quartermaine in the ABC soap opera General Hospital.

[4]: 117  For her role, Charleson received four Daytime Emmy Award for Outstanding Lead Actress in a Drama Series nominations: in 1980, 1982, 1983 and 1995.

[2] During her General Hospital years, Charleson starred alongside Deidre Hall and Colleen Zenk in the 1993 made-for-television movie Woman on the Ledge.