It reached number one on the Billboard Hot 100[1] and was certified triple platinum by the Recording Industry Association of America (RIAA).

[3] The song served as the lead single from Derulo's self-titled debut studio album, which was released on March 2, 2010, and reached number 11 on the Billboard 200.

While both attained peaks within the top 10 in multiple countries, "In My Head" became Derulo's first number-one single in the likes of Australia and the United Kingdom.

[5] the second single taken from the album, "It Girl" also achieved success, reaching the top five in Australia, New Zealand and the United Kingdom.

In April 2013, Derulo unveiled the lead single from his third studio album; Tattoos, "The Other Side" saw Derulo return to the top five in Canada for the first time since 2009, reaching number 17 in the United States and the top five in Australia and the United Kingdom.

In 2020, Derulo's single "Savage Love (Laxed – Siren Beat)" peaked at number one on the Billboard Hot 100, marking his first top 10 hit in five years.