[4][1] The site extensively covered allegations of ethically gray activities surrounding the Nike Oregon Project and coach Alberto Salazar, who was banned in 2019 for offenses related to doping.

[9] Johnson said about Rupp, “I think we should evaluate his career like everyone else but with more skepticism since one athlete is tied more closely to Alberto than anyone else.” LetsRun provided coverage and analysis of the doping allegations against Shelby Houlihan,[10][11] a prominent American middle-distance runner.

[12][13] A notable piece on Caster Semenya highlighted her XY chromosome configuration, a detail that the site contended was not widely covered in mainstream media.

[14] The article criticized the NYC Marathon's non-binary category, claiming it conflates gender identity with biological sex and discriminates against female athletes.

In 2015, following a viral post made by Mike Rossi justifying his children's absences from school while watching him run at the Boston Marathon, Robert Johnson wrote a 5,000 word article on LetsRun describing "overwhelming" evidence that Rossi had cheated in an earlier qualifying race, based in part on information discovered by various users and posted to the LetsRun message boards.

At the 2016 Rio Olympics, a journalist for the website, Jon Gault, asked Ethiopian medalist Feyisa Lilesa why he raised his hands above his head in an X at the finish line.

[20][21] The website covered Guatemalan runner Luis Grijalva's quest for American citizenship, and the challenges he faced regarding his participation in the 2020 Tokyo Olympics due to his DACA (Deferred Action for Childhood Arrivals) status.