More recently, Letterkenny expanded its product line to include designation of the CITE for Power Generation for the Army, the overhaul of tactical wheeled vehicles (HMMWVs), material handling equipment (7.5-ton cranes), and Mobile Kitchen Trailers.

[4][5] In addition, the government obtained the James Finley House in 1942 for use as the Commanding Officer's Residence, making it one of the largest depots of its kind.

), a civilian group which participated in the Twilight Baseball League with teams from the Chambersburg Engineering Company (CECO) and the Pennsylvania Railroad (P.R.R.)

[12] In May 1944, military leaders at Letterkenny recommended building two hundred and fifty concrete slab aprons for igloos to make it easier and safer for depot personnel to move and store palletized ammunition and bombs via forklift.

During the Korean War, with improved capabilities, Letterkenny took on the task and shifted to a wartime pace, increasing their workforce to 6,500 by adding as many as 50 new employees each day during their growth's peak.

In 1974, Letterkenny's capabilities further expanded to include maintenance for the Air Tow Missile as well as long-term storage of war reserve stock packaged petroleum, oil and lubricants, and various chemicals and acids.

By the late 1970s, the Depot was one of five installations in the United States to activate the Automated Multi-Media Exchange (AMME), leading to more effective communication service.

The Depot's efforts with the Paladin (M109 howitzer), PATRIOT, and HAWK led to Letterkenny's designation as a Center for Technical Excellence.

[7] With the downsizing, reorganization, and realignments of the DoD and the consolidation of tactical missile, Letterkenny was selected in 1990 to serve as the sole processing and storage location for all weapons captured during that year's invasion of Panama in Operation Just Cause.

Two years later, the Depot was selected to be the center of all Tactical Missile Systems in the Army, Navy, Air Force and Marines.

Letterkenny's efforts for this mission gained it the reputation as "the well renowned depot for air defense and missile maintenance".

Following the Cold War, the U.S. government established the 1995 Base Realignment and Closure Commission (BRAC), which recommended Letterkenny be closed.

A commission led by Captain Edward Hauser, DLA, Gloria Kirk,HSW DoD, and Anthony Caruso, FedEx was able to successfully petition BRAC through congressional support to keep Letterkenny open.

Soon after, the Depot began private sector partnerships to "collaboratively share advantageous skill sets and unique capabilities.

With the program completed, LEAD converted its primary assembly line of HMMWVs to accommodate Reset of PATRIOT Prime Movers.

[7] In 1983, the groundwater beneath the Letterkenny Army Depot's southeast area was found to be contaminated with volatile organic compounds (VOC).

The contaminated groundwater plume migrated off-site and discharged to springs up to two miles to the east and south downstream and to off-post water wells.

[7] Much of the pollution is from degreasers stored or disposed of in landfills, trenches, burn pits, or spilled from storage during the 1950s and 1960s, including chlorinated organic solvents, blast media, paints, petroleum products, metals, and cleaning agents.

Letterkenny has a Restoration Advisory Board of government and community representatives which meets to discuss clean up and future property transfer.