Since 1977 Ambartsumian has performed regularly in all the main cities of the Soviet Union and Eastern Europe as he was not permitted to accept invitations to travel to the West.
He has collaborated with conductors and composers such as Valery Gergiev, Vladimir Fedoseev, Maxim Shostakovich, Aram Khachaturian, Alfred Schnittke, and many others.
Ambartsumian devotes himself to contemporary Russian, Armenian and American Music and has made several important world premiers.
He has released several CDs, including music by Wieniawski, Sarasate, Brahms, Mendelssohn, Tchaikovsky, Vivaldi, Stravinsky, Bartók, Shostakovich, Schnittke, Bronner, Arutiunian and other contemporary composers.
His former students hold principal positions in major European orchestras in Germany, France, Portugal, and Denmark, and many have been prizewinners at international violin competitions.