Lewis Miller (July 24, 1829 – February 17, 1899) was an American businessman and philanthropist who made a fortune in the late 19th century as inventor of the first combine (harvester-reaper machine) with the blade mounted efficiently in front of the driver, to the side of the horse(s), rather than pulled behind.

His daughter Mina (1865–1947) married fellow Ohio inventor Thomas Alva Edison on February 24, 1886.

He devoted much of his wealth to public service and to charitable causes associated with the Methodist Episcopal Church, and was the inventor of the "Akron Plan" for Sunday schools, a building layout with a central assembly hall surrounded by small classrooms, a configuration Miller conceived with Methodist minister John Heyl Vincent and architect Jacob Snyder.

John Heyl Vincent collaborating was baptist layman B.F. Jacobs devised a system to encourage Sunday school work, and a committee was established to provide the International Uniform Lesson Curriculum, also known as the "Uniform Lesson Plan".

[3] The Lewis Miller Cottage, his residence at Chautauqua, is a National Historic Landmark and considered one of the first prefabricated structures in the United States.