[12] Growing up, he wanted to be a perfumer, but found it too mathematical,[13] and spent much of his childhood on Sophie-Anne's phone, which contained a number of video games, including a rudimentary digital audio workstation.

He then spent a period in New York,[7] at which, aged eleven,[14] he learned to play the drums; upon his return to Paris, he became the drummer for a band,[7] the Jools,[14] before buying himself a keyboard the following year.

"[7] Delhomme adopted the Lewis OfMan moniker around 2014;[15] SoundCloud had asked him what his artist name was, and he remembered that his brother had played a soccer video game in which his surname appeared in Spanish as "Del Hombre", prompting him to mention in passing that its English translation was "Of Man".

[16] He then released the single Nails Matching My Fit featuring Shanae, and in July 2022, he released Move Me, a collaboration with Carly Rae Jepsen, who had discovered Delhomme in September 2020 after a friend sent her a playlist; in an October 2022 interview with Paper, Delhomme stated that he wrote the song while living in Florence after spending a "special night" with someone, and that he wrote the track the day before a session with Jepsen.

[23] In an April 2017 interview with W, he stated that he was "really inspired" by Frank Ocean, Ennio Morricone, Lee Fields, and Jamie xx, further elaborating that:Frank Ocean is the greatest artist I ever known, his way to create is incredible, all the contrasts and mysteries you can find in his music are very interesting, I really love his album Blonde and ever more the video album Endless, which is for me an incredible performance of talent and standards exit.

[15]Under the name Lewis OfMan, he is since December 2023 on tour in France, Belgium, in the United States, Mexico and as well in Canada to promote his latest album Cristal Medium Blue.