Lees Priory was located near to Chatsworth House, in an area of the estate known as Carlton Lees: between the villages of Edensor and Beeley.

[1] The priory was occupied by Augustinian Canons Regular, and was dependent upon Rocester Abbey in Staffordshire.

[1] The priory is thought to have been founded before 1160, and dissolved between 1517 and 1540, but its exact status is unclear.

However, in 1517, there is reference to the "Prior of Lees", indicating, at least by that point, the establishment was a formal priory;[1] meaning the establishment had far greater Independence and a larger monastic population than a cell, which is directly dependent upon its mother church.

The priory did not escape King Henry VIII's Dissolution of the Monasteries.