Following her graduation she was assigned to People's Liberation Army Daily as a writer, under the pen name Xiao Li, during the Cultural Revolution.

On 13 January 1967, Li Na organized the "Revolutionary Rebel Commando " and posted a large-character poster of "Where is the People's Liberation Army News Going" to expose Hu Chi (the acting president of Xinhua News Agency and a member of the Cultural Revolution Group within the PLA), Song Qiong, Yang Zicai and the other leaders about the direction of motion of the newspaper.

[6] In January of the same year, due to her being the daughter of Mao Zedong and Jiang Qing, she took up the post of head of the Central Cultural Revolution Team.

On 23 August 1967, Li Xiao's third big-character poster was published: "Repeatedly, anti-conservative, and vowed to carry the revolution to the end!"

[7] On 9 September 1976, after years of ill health, Mao Zedong suffered a series of heart attacks and died at the age of 82.

When Li Na finally left the memorial hall, she held the staff tightly and said with tears in her eyes, "Thank you for taking care of my dad for 30 years".

[13] On 20 May 2015, Li Na visited Northern Shaanxi, the birthplace of the Chinese Communist Revolution, to attend the ceremony honoring her father.

In 1984, she was remarried to Wang Jingqing, a bodyguard to Mao Zedong and Chief of Staff of the Nujiang Army Division of Kunming Military Region.