Sharp made his debut in the 1980s for the science fiction magazine 2000 AD after a year's apprenticeship with Don Lawrence, artist on the Dutch comic Storm.

Later he co-created the Wildstorm series The Possessed with writer Geoff Johns,[2] and a strip for Heavy Metal magazine, entitled "A-crazy-A" featuring Playboy model Tiffany Taylor – for which he provided the art and script.

Event Horizon featured art by Glenn Fabry, Brian Holguin, Ashley Wood, Simon Bisley, Alan Grant, Steve Niles, Emma Simcock-Tooth, Ali Powers, Kev Crossley, Lee Carter and Dave Kendall.

[3] Sharp went on to illustrate the controversial and critically well-received DC Vertigo comic Testament written by Douglas Rushkoff,[5][6] and the Countdown-related title, Lord Havok and The Extremists with writer Frank Tieri.

A recent exhibition was held in the Crompton Arms, a Derby public house and alternative art gallery, featuring the work of Sharp, Ali Pow3rs, Adam Dutton and Chris Tree.

With Guinness officials on hand to monitor their progress, writer Mark Millar began work at 9am scripting a 20-page black and white Superior comic book, with Sharp and the other artists appearing on stage throughout the day to work on the pencils, inks, and lettering, including Dave Gibbons, Frank Quitely, John Romita Jr., Jock,[14] Doug Braithwaite, Ian Churchill, Duncan Fegredo, Simon Furman, David Lafuente, John McCrea, Sean Phillips and Liam Sharp,[15] who all drew a panel each, with regular Superior artist Leinil Yu creating the book's front cover.

Liam was awarded a wrought-Iron and mosaic star in the city's #MadeInDerby2 campaign, which can be found outside the Standing Order pub, near the front door of the house where Joseph Wright lived in Derby's cathedral quarter.