The lands that now make up this municipality were inhabited by Nutabe and Tahamí communities at the time of the conquest, who fiercely defended themselves against Spanish invaders.

Liborina was founded on March 7, 1832, and on September 25 of the same year, the procedures for the creation of the parish and its separation from Sacaojal were carried out.

Don Vicente Londoño, one of the municipality's founders, was the first mayor and commissioner, contributing his own economic resources to the construction of houses and the market fair.

In addition to its main urban area, Liborina has jurisdiction over the following corregimientos (according to the departmental management): Historical Population: Total Population (2018): 10,028 inhabitants[4] According to the 2005 census data presented by DANE, the ethnic composition of the municipality is: Hidroituango Project: Liborina is one of the municipalities involved in the Hidroituango hydroelectric project, finished in 2018.

Initially, the PCH Liborina will be built for electricity generation, with an installed capacity of 4.9 MW, capturing the waters of the Juan García stream through a small dam, a conduit, and a powerhouse located in the San Diego corregimiento.