Lignana is a comune (municipality) in the Province of Vercelli in the Italian region Piedmont, located about 60 kilometres (37 mi) northeast of Turin and about 6 kilometres (4 mi) southwest of Vercelli.

Lignana borders the following municipalities: Crova, Desana, Ronsecco, Salasco, Sali Vercellese, and Vercelli.

Tenuta Veneria, together with Selve (frazione of the comune of Salasco), was a filming location for Bitter Rice, a 1949 movie starring Silvana Mangano.

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