[3][4] Lijomol made her acting debut in the highly acclaimed Malayalam film, Maheshinte Prathikaaram in 2016.

[1][5] She then played the second female lead in the commercially successful film Kattappanayile Rithwik Roshan in the same year.

[5][6] In her third film, Honey Bee 2.5 (2017), she played the role of a personal make-up artist of actress Bhavana.

[7] She then starred in Street Lights (2018) with Mammootty before making her Tamil cinema debut with Sivappu Manjal Pachai (2019) opposite Siddharth.

[8][9] She was critically acclaimed for portraying the anguish of a primitive Irular tribe, Senggeni in Jai Bhim, co-starring actor Suriya.