Nimisha made her acting debut with the film Thondimuthalum Driksakshiyum directed by Dileesh Pothan.

[1] She won the Kerala State Film Award for Best Actress in 2018 for her performance in Oru Kuprasidha Payyan and Chola.

[3] Nimisha started her acting career with the film Thondimuthalum Driksakshiyum, directed by Dileesh Pothan.

[4] She then played the lead role in editor B. Ajithk and Rajeev Ravi's 'Eeda'.

In 2022 she was a part of Oru Thekkan Thallu Case, Innale Vare and Heaven.