Lilbourn is a city in New Madrid County, Missouri, United States.

[4] The community was named for Lilbourn Lewis, an early settler.

The St. Louis Southwestern Railway passes through the south part of the community.

[6] According to the United States Census Bureau, the city has a total area of 0.94 square miles (2.43 km2), all land.

[7] As of the census[9] of 2010, there were 1,190 people, 489 households, and 320 families living in the city.

30.5% of all households were made up of individuals, and 13.5% had someone living alone who was 65 years of age or older.

27.7% of all households were made up of individuals, and 15.6% had someone living alone who was 65 years of age or older.