[7]: 325 and was appointed director of the department of biological chemistry at the Psychiatric Institute of the New York State Hospital the same year.
[8] Her writings from this era include publications in The New Republic where she wrote on cancer[9][10] and drug addiction.
[11][12] In 1925 Segal became a member of the Arcturus expedition that was led by William Beebe[13][14] where her official title was "Associate in charge of special problems".
[22] In interviews given at the end of the expedition, Beebe credited the four women on the ship, Segal along with Ruth Rose, Marie Poland Fish, Helen Tee-Van,[23] for his success.
[24] In 1928, William K. Gregory published the results of their work on the Arcturus expedition, with an acknowledgement to Segal's contribution on the project.