He had entered the field of journalism shortly after his marriage and during the early years of his career wrote for the New York Sun and edited the Albany Express.
Frederick White became famous in the West and throughout the country as an editorial writer, critic, and essayist for the Denver Post, under the initials F.W.W.
After the deaths of her parents, Frederick in February 1917 and Catherine in March 1918, and the end of her marriage, Spencer returned to Denver.
The Pageant of Colorado (music by Charles Wakefield Cadman), was presented in Denver in May 1927 with a cast of 1500, and was said to have been the largest indoor spectacle ever produced in the West.
A story in Spencer's poem Blue Feather inspired a collaboration with Charles Sanford Skilton on the opera The Sun Bride, produced by the National Broadcasting Company on April 17, 1930.
After 1930, Spencer's efforts turned from writing to getting poems and translations already written published in book form or republished in magazines.
In 1944, she and her brother Frank E. White sold the family home at 1490 Stuart Street in Denver and moved to Oceanside, California.