On 7 November 1888 at St Mary's Anglican Church in Caulfield, she married 33-year-old sheepmaster David Alexander Skene.
[1] Unable to make the second payment on the property he was buying when the banks collapsed in the early 1890s, her husband was forced to work as a station-manager in New South Wales.
In the face of drought and the high cost of fodder, they sold out in 1906 and moved to Melbourne, where David set up as a woolbroker and stock-and-station agent.
In 1915, she became the honorary manager and storekeeper of the Melbourne-based Home Hospital situated in the Government House.
[1] Skene was appointed a Member of the Order of the British Empire for her contribution to the Red Cross during World War I.