From New York City,[1][2] McInerny began acting at elementary school when she was eight years old.

After high school she attended college in Vermont studying for a degree in performing arts.

[3] In 2022, McInerny was seen in Palm Trees and Power Lines which premiered at the Sundance Film Festival and later saw her nominated for Best Breakthrough Performance at the 38th Independent Spirit Awards.

[8] In November 2022 she made her New York stage debut in Bess Wohl written play Camp Siegfried, directed by David Cromer at Second Stage's Tony Kiser Theater.

[10] In 2023 she was cast in a contemporary adaptation of the 1958 Françoise Sagan novel Bonjour Tristesse, appearing alongside Claes Bang and Chloë Sevigny.