Limestone County is included in the Huntsville, AL Metropolitan Statistical Area.

Limestone County was established by the Alabama Territorial legislature on February 6, 1818.

[1] On November 27, 1821, the Alabama State legislature passed an Act that altered the boundary of Limestone County to include the area east of the mouth of the Elk River with the Tennessee River.

As of the 2020 United States census, there were 103,570 people, 32,020 households, and 23,919 families residing in the county.

As of the 2010 census,[15] there were 82,782 people, 31,446 households, and 22,876 families living in the county.

As of the 2000 census,[16] there were 65,676 people, 24,688 households, and 18,219 families living in the county.

According to the census of 2000, the largest ancestry groups in Limestone County were English 66.31%, Scots-Irish 15.12%, and African 13.33% There were 24,688 households, 34.80% had children under the age of 18 living with them, 60.00% were married couples living together, 10.40% had a female householder with no husband present, and 26.20% were non-families.

Limestone County comprises the Thirty-Ninth Judicial Circuit of Alabama.

The last Democrat to win the county in a presidential election is Jimmy Carter, who won it by an absolute majority in 1980.

School districts include:[20] Tertiary education: Huntsville International Airport (HSV) is the nearest major commercial airport, 23 miles east.

Nashville Airport (BNA) is approximately 104 miles north.

The least most populous town in Limestone county is Mooresville with 47 people in 2020.