[3] Its name is in honor of John Williams Walker, the first U.S. senator elected from Alabama.

[1] Walker County comprises the entirety of the Jasper, AL Micropolitan Statistical Area.

[1] Walker County has sites listed on the National Register of Historic Places.

[6] As of the census of 2020, there were 65,342 people, 25,153 households, and 17,410 families residing in the county.

As of the census of 2010, there were 67,023 people, 26,571 households, and 18,741 families living in the county.

As of the census of 2000, there were 70,713 people, 28,364 households, and 20,478 families living in the county.

[16] In 2000 the largest reported ancestry groups in Walker County, AL were: There were 28,364 households, 30.70% had children under the age of 18 living with them; 56.30% were married couples living together, 11.90% had a female householder with no husband present, and 27.80% were non-families.

Local officials have described coal mining as "literally at the core" of the county's economy.

[17] Walker County is home to the William B. Bankhead National Forest and Lewis Smith Lake, in addition to the Alabama Mining Museum.