She worked at IBM prior to her retirement on December 31, 2014, where she was the senior vice president of Enterprise Transformation.
[2][3] Her previous positions at IBM included senior vice president and group executive in the company's Storage Systems Group and general manager of the S/390 Division.
She was elected a member of the National Academy of Engineering in 1997 for computer product development including transformation from hierarchical mainframes to more robust enterprise network server architectures.
In 2018, St. John's University dedicated a new computer lab, called the Sanford Family Cyber Security Lab, in honor of Sanford and her family.
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