As of January 2020[update], it had over 46,000 local clubs and more than 1.4 million members (including the youth wing Leo) in more than 200 countries and geographic areas around the world.

The Association went international in 1920 when Border Cities Lions Clubs in Windsor, Canada, was established.

It subsequently evolved as an international service organization under the guidance and supervision of its secretary, Melvin Jones.

After contacting similar groups around the United States, an organizational meeting was held on June 7, 1917, in Chicago.

The Business Circle subsequently joined one of the invited groups, the "International Association of Lions Clubs" and at a national convention held in Dallas, Texas, later that year, those who were assembled: (1) adopted a Constitution, By-Laws, Code of Ethics and an Emblem; (2) established as a main tenet "unselfish service to others", (3) unanimously elected Woods as its first president, effectively securing his leadership for the first two years of the existence of the International Association of Lions, and (4) selected Jones to serve as the organization's secretary-treasurer.

Some of this is donated in reaction to events such as the 2004 Indian Ocean earthquake and the 2013 Typhoon Haiyan (Yolanda).

It has allocated over US$11 million in 10 countries for eye surgeries, medical training, distribution of Zithromax and tetracycline, and sanitary services.

A Lions Club chooses its members diligently as it requires time and financial commitments.

[28] The organization expanded internationally on 12 March 1920, when a club opened in Windsor, Ontario, Canada.

An international convention is held annually in cities across the globe for members to meet other Lions, elect the coming year's officers, and partake in the many activities planned.

[31] At the convention, Lions can participate in elections and parades, display and discuss fundraisers and service projects, and trade pins and other souvenirs.