[1][2] Bero is a Professor of Medicine and Public Health and the Chief Scientist of the Center for Bioethics and Humanities at the University of Colorado.

[3] Bero has received multiple awards for her extensive mentoring of high school students to junior faculty.

[1][10] A fellowship from the Pew Charitable Trust enabled her to make a transition from the basic sciences to health policy.

[11] She is a co-author of The Cigarette Papers,[12] a collection of documents published in 1996 that played a key role in litigation of tobacco companies.

[6] Bero was a member of the Institute of Medicine Committee on Conflict of Interest in Medical Research, Education and Practice, which published its report in 2009.

[2] Along with Robert Krughoff and George Loewenstein, she co-authored a minority opinion entitled "Model for broader disclosure" (Appendix F) arguing that given the "serious limitations in the accuracy, completeness, comparability, and timeliness of conflict of interest information reported to institutions and to the public," the IOM recommendations did not go far enough.

Their proposed model was based on the development of a database centralizing data on academics' potential conflicts of interest.

[14] In 2014 Lisa was appointed the inaugural Chair of Medicines Use and Health Outcomes in the Faculty of Pharmacy and Charles Perkins Centre at the University of Sydney.

[16] Bero was an editor of the Cochrane Collaboration Review Group on Effective Professional Practice and Organization of Care from the late 1990s.