She is known for producing whimsical commercial design for school supplies and other products that are primarily marketed to children and young adolescents.
[4] After moving from the Detroit, Michigan, area to Tucson, Arizona, in the 1970s to study art at the University of Arizona, she founded the children's jewelry company Sticky Fingers, operating at first from a guest house in Frank's back yard, which became Lisa Frank Inc. circa 1979 when she was 24.
[8] Frank's artwork features rainbow and neon colors and stylized depictions of animals, including dolphins, pandas, and unicorns.
[12][13][4] In the late 2010s and early 2020s, during a wave of nostalgia for the 80s and 90s, Frank's designs experienced a resurgence in popularity and several collaborations were developed featuring her artwork.
Green, who from 1990 to October 2005 was president and chief executive officer of Lisa Frank Incorporated.