[3] Lisa Selesner was born on May 26, 1978, in Monaco to an American mother and a father of French and Chinese descent.

[4][5] She stated that she shortened her surname from Selesner to the initial "S" because after moving to Hong Kong in 2000, "no one could pronounce it".

[3] In Hong Kong, she became a top model who appeared in advertisements for Citibank, De Beers and Olay.

She is the founder of the monthly beauty box subscription 'Glamabox' which is provided in China, Taiwan, Hong Kong and Singapore.

[6] On April 6, 2010, Lisa S. married Daniel Wu in South Africa, after eight years of dating.