She led the network's comprehensive coverage of the murder conspiracy trial of Carolina Panthers wide receiver Rae Carruth in December 2000 through January 2001.

Salters was also ESPN's reporter at the 2002 FIFA World Cup in South Korea and Japan, where she broke the news on the U.S. National Team's starting lineup a day before its first match in against Portugal.

During the build-up to Operation Iraqi Freedom through the commencement of the Iraq War, Salters covered sports-related stories in and around U.S. Central Command in Qatar for Outside the Lines, SportsCenter and ESPNEWS.

[8] She returned to the war zone in 2004 when ESPN took SportsCenter on the road and broadcast live from Camp Arifjan, a U.S. Army base in Kuwait.

Six years later, ESPN announced a new Monday Night Football commentating team which included Salters as sideline reporter and joined by Joe Tessitore and Booger McFarland.

In 2020, Steve Levy, Brian Griese, and Louis Riddick replaced Tessitore and McFarland to join Salters on MNF.

Salters was born in King of Prussia, Pennsylvania[2] and graduated from Penn State University in 1988 with a bachelor's degree in broadcast journalism.

She played guard for the Lady Lions basketball team from 1986 to 1987, where Salters holds the distinction of being the shortest player in school history at 5 feet 2 inches (1.57 m).