After a short study of graphical design at the Santa Monica College of Art in California, Lise Myhre started her career as an artist, earning money illustrating CD covers and T-shirts.
From 1997, Myhre was given her own page in Larsons Gale Verden, "Den svarte siden" (English: the Black Side/Page), and this developed into Nemi.
Nemi is today published in approximately 60 different newspapers, magazines and websites in Norway, Sweden, Denmark, Finland.
Lise Myhre has also illustrated poems by Edgar Allan Poe and André Bjerke.
She was married to musician ICS Vortex (Simen Hestnæs), and they have a son, Storm, born 2007.